Researchers later found pravado-line to become nephrotoxic. In order to determine the particular system whereby this proved helpful, research workers developed as well as synthesized conformationally controlled aminoalkylindole analogs. From this program, research workers found w-i-n fifty-five, 212 to become fairly powerful analgesic, however Sterling-Winthrop dropped its research about aminoalkylindoles any time that became obvious that w-i-n 55, 212-2 as well as associated similar aids had been.
